Strict Standards: Non-static method AL_HELPER::SetupPaths() should not be called statically in /home/cheaphos/public_html/endo/init.php on line 66

Strict Standards: Non-static method AL_CATEGORY::GetCategoryArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 77

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Strict Standards: Non-static method AL_CATEGORY::GetSubCatsArray() should not be called statically in /home/cheaphos/public_html/endo/admin/includes/classes/class.category.php on line 496

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/includes/classes/class.categories.php on line 41

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 269

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 328

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/includes/classes/class.blog.php on line 153

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/includes/classes/class.author.php on line 139

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 999

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 1000

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/includes/classes/class.template.php on line 117

Deprecated: Function ereg_replace() is deprecated in /home/cheaphos/public_html/endo/includes/classes/class.template.php on line 243

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 86

Deprecated: Non-static method AL_HELPER::PageLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 95

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 498

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 86

Deprecated: Non-static method AL_HELPER::PageLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 95

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 498

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 86

Deprecated: Non-static method AL_HELPER::PageLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 95

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 498

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 86

Deprecated: Non-static method AL_HELPER::PageLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 95

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 498

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 86

Deprecated: Non-static method AL_HELPER::PageLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 95

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 498

Deprecated: Function eregi() is deprecated in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 86

Deprecated: Non-static method AL_HELPER::PageLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PageHeader.php on line 95

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 498

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/ArticleOptionsPanel.php on line 60

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/templates/Slick/Panels/ArticleOptionsPanel.php on line 60

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/ArticleOptionsPanel.php on line 63

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/templates/Slick/Panels/ArticleOptionsPanel.php on line 63

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/ArticleOptionsPanel.php on line 68

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/templates/Slick/Panels/ArticleOptionsPanel.php on line 68

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/ArticleOptionsPanel.php on line 81

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/RootArticleCategoriesPanel.php on line 77

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/ViewArticlePanel.php on line 715

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::AuthorLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 503

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 467

Deprecated: Non-static method AL_HELPER::GetRelativeDate() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 496

Deprecated: Non-static method AL_HELPER::ShortDate() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 264

Deprecated: Non-static method AL_HELPER::GetCategoryListCVS() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/ViewArticlePanel.php on line 75

Deprecated: Non-static method AL_HELPER::CategoryLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 284

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 586

Deprecated: Non-static method AL_HELPER::GetRatingBar() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/ViewArticlePanel.php on line 76

Deprecated: Non-static method AL_HELPER::GetGlossaryTerms() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 618

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 701

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 708

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 708

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 715

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/includes/classes/class.article.php on line 734

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PopularArticlesPanel1.php on line 96

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PopularArticlesPanel1.php on line 96

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PopularArticlesPanel1.php on line 96

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PopularArticlesPanel1.php on line 96

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::ArticleLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PopularArticlesPanel1.php on line 96

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::_MakeArticleURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 435

Deprecated: Non-static method AL_HELPER::_SwapLetters() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 401

Deprecated: Function eregi_replace() is deprecated in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 403

Deprecated: Non-static method AL_HELPER::AuthorLink() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/templates/Slick/Panels/PopularAuthorsPanel1.php on line 79

Deprecated: Non-static method AL_HELPER::_MakeURLSafe() should not be called statically, assuming $this from incompatible context in /home/cheaphos/public_html/endo/admin/includes/classes/class.helper.php on line 467
Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in pulp tissue from painful and healthy human teeth
Article Options
Categories


Search


Advanced Search



This service is provided on D[e]nt Publishing standard Terms and Conditions. Please read our Privacy Policy. To enquire about a licence to reproduce material from endodonticsjournal.com and/or JofER, click here.
This website is published by D[e]nt Publishing Ltd, Phoenix AZ, US.
D[e]nt Publishing is part of the specialist publishing group Oral Science & Business Media Inc.

Creative Commons License


Recent Articles RSS:
Subscribe to recent articles RSS
or Subscribe to Email.

Blog RSS:
Subscribe to blog RSS
or Subscribe to Email.


Azerbaycan Saytlari

 »  Home  »  Endodontic Articles 1  »  Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in pulp tissue from painful and healthy human teeth
Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in pulp tissue from painful and healthy human teeth
Results.



All patients in the pain group reported a VAS score of 5 or more at their initial appointment and then reported a score of 0 on their second visit, indicating total relief of pain following pulpectomy regardless of the intracanal treatment. This also confirmed the diagnosis of pulpal pain.

Neuropeptide levels in pulp tissue samples.
Both SP-Ir and CGRP-Ir were present in all samples with NKA-Ir in 96% of the 66 pulp samples. The mean concentrations of SP-Ir, NKA-Ir and CGRP-Ir were significantly higher in pulp tissue from painful teeth compared with non-painful teeth (Table 1, Fig. 1). Notably, the concentration of NKA was more than four times higher in painful teeth than in non-painful teeth. The mean concentration of CGRP was much higher than both SP-Ir and NKA-Ir in both painful and non-painful teeth.

Neuropeptide concentration (ngg-1) in pulp tissue from painful and non-painful teeth
Figure 1.
Neuropeptide concentration (ngg–1) in pulp tissue from painful and non-painful teeth.


There were moderate but statistically significant correlations between the levels of the three neuropeptides in both painful and non-painful teeth. In painful teeth, Pearson’s product moment correlation coefficient ( r ) for SP-Ir/NKA-Ir was r = 0.60 ( P < 0.0001), SP-Ir/CGRP-Ir was r = 0.54 ( P < 0.0001) and NKA-Ir/CGRP-Ir was r = 0.42 ( P = 0.004). The correlations were stronger in non-painful teeth; SP-Ir/NKA-Ir was r = 0.59 ( P = 0.006), SP-Ir/CGRP-Ir was r = 0.72 ( P < 0.0001) and NKA-Ir/CGRP-Ir was r = 0.61 ( P = 0.004).
The effect of age, gender, tooth location, tooth type (incisor, canine, premolar and molar) and smoking on levels of SP-Ir, NKA-Ir and CGRP-Ir in the pulp tissue was studied. Smoking was the only variable, apart from pain, which emerged from the stepwise regression analysis as having a relationship with neuropeptide concentration. Bivariate analysis indicated that the levels of CGRP-Ir, but not SP-Ir or NKA-Ir, were significantly ( P = 0.02) higher in smokers compared with non-smokers (Table 2).

Mean concentrations of SP-Ir, NKA-Ir and CGRP-Ir in painful teeth from smokers and non-smokers
Table 2. Mean (SD) concentrations of SP-Ir, NKA-Ir and CGRP-Ir in painful teeth from smokers and non-smokers.

Regression analysis showed a significant association between the severity of pain recorded using the VAS and the levels of SP-Ir ( P = 0.036) and NKA-Ir ( P < 0.001) but not CGRP-Ir ( P = 0.313).