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T. Ataoglu, M. Üngör, B. Serpek, S. Haliloglu, H. Ataoglu & H. Ari Departments of Periodontology, Endodontics, and Maxillofacial Surgery, Dentistry Faculty Department of Biochemistry, Veterinary Faculty, Selcuk University, Konya, Turkey
Aim. The aim of this study was to determine IL-1 and TNF- levels in periapical exudates and to evaluate their relationship with clinical and radiological findings.
Conclusions. It is apparent that the progression of periapical granulomas is accompanied by the rate at which their surrounding bone is destroyed. The results of the present study suggest that IL-1is more important than TNF-in periapical bone resorbing activity. Within the limitations of this study, it is concluded that periapical exudate levels of both cytokine are not able to reflect periapical disease state.
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