B. R. Dorn, L. J. Harris, C. T. Wujick, F. J. Vertucci & A. Progulske-Fox
Center for Molecular Microbiology, Department of Oral Biology,
Department of Endodontics, College of Dentistry, University of Florida, Gainesville, FL, USA.
The objective of this study was to determine whether laboratory strains and clinical isolates of microorganisms associated with root canal infections can invade primary cultures of cardiovascular cells.
Of the laboratory and clinical strains tested, only P. endodontalis ATCC 35406 was invasive in an antibiotic protection assay using HCAEC and CASMC. Invasion of P. endodontalis ATCC 35406 was confirmed by transmission electron microscopy.